Peter C. Kouretas, M.D., Ph.D.

Current Titles:
Staff Surgeon, Primary Children's Medical Center
Assistant Professor of Surgery, Division of Cardiothoracic Surgery, University of Utah School of Medicine

Clinical Interests:
Pediatric Heart Surgery
Mechanical Circulatory Support Device Implantation
Heart and Lung Transplantation

Research Interests:
Preservation of endothelial function following ischemia/reperfusion injury
Research and development of pediatric ventricular assist devices
Stem cell therapy in cardiomyopathy and congenital heart disease

Society Memberships:
American College of Surgeons (candidate member)
Harry H. Mueller/R. Scott Jones Surgical Society
CTSnet
American Medical Association
American Physiologic Society
Society for Experimental Biology and Medicine
American College of Cardiology-Affiliate
International Society for Heart and Lung Transplantation-Member
Association for Academic Surgery
Thoracic Surgery Residents Association
AHEPA

Pertinent Publications:
1. Myers JL, Petit M, Domkowski P, Kouretas PC, Yu A, Cockerham J, Wang Y, Hopkins RA: “Regional Pulsatile Hemodynamic Response to cGMP in the Neonatal and Infant Pig Pulmonary Arterial Circulation,” Surgical Forum, 46:289-292, 1995.

2. Kim YD, Chen B, Beauregard J, Kouretas PC, Thomas G, Farhat M, Myers AK, Lees DE:. “17 b Estradiol Prevents Dysfunction of Canine Coronary Endothelium and Myocardium and Reperfusion Arrhythmias After Brief Ischemia/Reperfusion,” Circulation, 94:2901-2908, 1996.

3. Wizorek JJ, Myers JL, Kouretas PC, Wang YN, Myers AK, Cockerham JT, Hopkins RA: “Endothelin-1 Acts Upon Endothelin-A Receptors at the Level of the Distal Pulmonary Arterioles to Induce Pulmonary Hypertension in the Neonatal Pig,” Surgical Forum, 47:324-328, 1996.

4. Myers JL, Wizorek JJ, Myers AK, Yankah E, Pettit MT, Kouretas PC, Dalton HJ, Wang YN, Hopkins RA: “Pulmonary Arterial Endothelial Dysfunction Potentiates Hypercapnic Vasoconstriction and Alters the Response to Inhaled Nitric Oxide,” The Annals of Thoracic Surgery, 62:1677-84, 1996.

5. Kouretas PC, Kim YD, Myers AK, Cahill PA, Wang YN, To LN, Myers JL, Sitzmann JV, Wallace RB, Hannan RL: “Heparin and Non-Anticoagulant Heparin Increase Nitric Oxide Levels in the Coronary Circulation After Ischemia- Reperfusion Injury,”Surgical Forum of the American College of Surgeons, 48: 254-256, 1997.

6. Myers JL, Wizorek JJ, Myers AK, O’Donoghue M, Petit, MT, Kouretas PC, Dalton HJ, Wang Y, Hopkins, RA: “Maturation Alters the Pulmonary Arterial Response to Hypoxia and Inhaled Nitric Oxide in the Presence of Endothelial Dysfunction,” The Journal of Thoracic and Cardiovascular Surgery, 113:270- 277, 1997.

7. Kouretas PC, Myers AK, Kim YD, Cahill PA, Myers JL, Wang YN, Sitzmann JV, Wallace RB, Hannan RL: “Heparin and Non-Anticoagulant Heparin Preserve Regional Myocardial Contractility After Ischemia-Reperfusion Injury: Role of Nitric Oxide,” The Journal of Thoracic and Cardiovascular Surgery, 115:440-449, 1998.

8. Soloman AJ, Kouretas PC, Hopkins RA, Katz NA, Wallace RB, Hannan RL: “Early Discharge of Patients with New-Onset Atrial Fibrillation After Cardiovascular Surgery,” American Heart Journal, 135(4):557-563, 1998.

9. Kim YD, Farhat MY, Myers AK, Kouretas PC, DeGroot KW, Pacquing A, Ramwell PW, Suyderhoud JP, Lees DE: “17- b Estradiol Regulation of Myocardial Glutathione and its Role in Protection Against Myocardial Stunning in Dogs,” Journal of CardiovascularPharmacology, 32:457-465, 1998.

10. Kouretas PC, Kim YD, Cahill PA, Myers AK, To LN, Wang YN, Wallace RB, Kron IL, Hannan RL: “Heparin Preserves Nitric Oxide Activity in Coronary Endothelium During Ischemia-Reperfusion Injury,” The Annals of Thoracic Surgery, 66:1210-1215, 1998.

11. Kouretas PC, Hannan RL, Kapur NK, Hendrickson RJ, Redmond EM, Myers AK, Kim YD, Cahill PA, Sitzmann JV: “Non-Anticoagulant Heparin Increases Endothelial Nitric Oxide Synthase Activity: Role of Inhibitory Guanine Nucleotide Proteins,” Journal of Molecular and Cellular Cardiology, 30:2669-2682, 1998.

12. Kouretas PC, Kim YD, Cahill PA, Myers AK, To LN, Wang YN, Sitzmann JV, Hannan RL: “Non-Anticoagulant Heparin Prevents Coronary Endothelial Dysfunction After Brief Ischemia-Reperfusion Injury in the Dog,” Circulation, 99:1062-1068, 1999.

13. Hannan RL, John MC, Kouretas PC, Hack BD, Matherne GP, Laubach VE: “Deletion of Endothelial Nitric Oxide Synthase Exacerbates Myocardial Stunning in an Isolated Mouse Heart Model,” Journal of Surgical Research, 93:127-132, 2000.

14. Cope JT, Fraser GD, Kouretas PC, Kron IL: “Complete versus partial atrioventricular canal: equal risks of repair in the modern era,” Annals of Surgery , 236(4):514-520, 2002.

15. Horstman DJ, Fischer LG, Kouretas PC, Hannan RL, Rich GF: “Role of Nitric Oxide in Heparin-Induced Attenuation of Hypoxic Pulmonary Vascular Remodeling,” Journal of Applied Physiology,92(5):2012-2018,2002.

16. Kouretas PC, Vial CM, Ross M, Bernstein D, Miller JL, Robbins RC, Reitz BA: “Pediatric Heart Transplantation: A Three Decade Experience at Stanford,” Circulation, In Preparation.

17. Kouretas PC, Ross M, Reitz BA, Robbins RC, Gamberg P, Miller J, Chin C, Bernstein D: “10 and 20-Year Long-Term Survival after Pediatric Orthotopic Heart Transplantation ,” The Journal of Heart and Lung Transplantation, In Preparation.